EDS Information

EDS Information

Ehlers-Danlos Syndrome results from a genetic mutation of collagen, causing widespread clinical manifestations due to collagen’s important role in supporting skin, joints, blood vessels, various tissues and other organs¹.  Symptoms of EDS vary by type and individual, but range from mild joint hypermobility to life threatening complications.  Classical Type (what I have)  is characterized by increased skin involvement, resulting in smooth, velvety skin that is hyperelastic (easily stretched) and fragile with uncommon scarring patterns in addition to the symptoms of Hypermobility Type.²

Symptoms include (but are not limited to):³

  • recurrent joint dislocations or subluxations with minimal trauma
  • degenerative joint disease
  • chronic pain
  • autonomic dysfunction
  • easy bruising
  • functional bowel disorders
  • hypotonia
  • chronic fatigue
  • muscle cramps
  • osteoarthritis
  • aortic root dilation

Below are the symptoms EDS causes in me:

  • recurrent joint dislocations, specifically the patellas, shoulders and fingers
  • chronic pain
  • easy bruising
  • smooth, velvety skin
  • abnormal scarring patterns
  • autonomic dysfunction, specifically with temperature regulation and heart rate
  • GI issues
  • osteopenia (low bone density)
  • juvenile degenerative disc disease
  • hypermobile joints
  • decreased proprioception ability

 

References

  1. Clayton HA, Cressman EK, Henriques DY (2013) Proprioceptive sensitivity in Ehlers-Danlos syndrome patients. Exp Brain Res 230:311–321
  2. Malfait F, Wenstrup R, De Paepe A. Ehlers-Danlos Syndrome, Classic Type. 2007 May 29 [Updated 2011 Aug 18]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016.
  3. Levy HP. Ehlers-Danlos Syndrome, Hypermobility Type. 2004 Oct 22 [Updated 2016 Mar 31]. In: Pagon RA, Adam MP, Ardinger HH, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2016